PUBLICATION LIST, (*, corresponding author) Impact factor(IF) ; Citation index(CI)
Original paper:
2024
Hung CJ, Tsai CT, Rahaman SM, Yamanaka A, Seo W, Yokoyama T, Sakamoto M, *Ono D. Neuropeptidergic input from the lateral hypothalamus to the suprachiasmatic nucleus alters the circadian period in mice. J Neurosci 2024, e0351242024; https://doi.org/10.1523/JNEUROSCI.0351-24.2024.
Thang PX, Abe Y, Mukai Y, Ono D, Tanaka KF, Ohmura Y, Wake H, *Yamanaka A, Glutamatergic signaling from MCH neurons: A requirement for memory regulation, but not for metabolism control. PNAS Nexus, 2024, 3(7), 275, https://doi.org/10.1093/pnasnexus/pgae275.
Fujioka Y, Kawai K, Endo K, Ishibashi M, Iwade N, Tuerde D, Kaibuchi K, Yamashita T, Yamanaka A, Katsuno M, Watanabe H, Sobue G, Ishigaki S. Stress-impaired reward pathway promotes distinct feeding behavior patterns. Front in Neurosci, 2024; 18. https://doi.org/10.3389/fnins.2024.1349366.
Uchida R, Mukai Y, Amano T, Sakimura K, Itoi K, Yamanaka A, Minami M. Chronic pain enhances excitability of corticotropin-releasing factor-expressing neurons in the oval part of the bed nucleus of the stria terminalis. Mol Brain, 2024;17(1):22. doi: 10.1186/s13041-024-01094-6.
Heiss JE, Zhong P, Lee SM, Yamanaka A, Kilduff TS. Distinct lateral hypothalamic CaMKIIα neuronal populations regulate wakefulness and locomotor activity. Proc Natl Acad Sci U S A 2024;121(16):e2316150121. doi: 10.1073/pnas.2316150121.
Braun A, Manavis J, Yamanaka A, Ootsuka Y, Blumbergs P, Bobrovskaya L. The role of orexin in Parkinson's disease. J Neurosci Res. 2024; 102(3):e25322. doi: 10.1002/jnr.25322. Review
Narai E, Yoshimura Y, Honaga T, Mizoguchi H, Yamanaka A, Hiyama TY, Watanabe T, Koba S. Orexinergic neurons contribute to autonomic cardiovascular regulation for locomotor exercise. J Physiol. 2024 Feb 21. doi: 10.1113/JP285791.
2023
*Yamaguchi H, Murphy KR, Fukatsu N, Sato K, Yamanaka A, *de Lecea L. Dorsomedial and preoptic hypothalamic circuits control torpor. Curr Biol, 2023; 33(24):5381-5389.e4. IF=10.9; CI=-
Kawana Y, *Imai J, Morizawa YM, Ikoma Y, Kohata M, Komamura H, Sato T, Izumi T, Yamamoto J, Endo A, Sugawara H, Kubo H, Hosaka S, Munakata Y, Asai Y, Kodama S, Takahashi K, Kaneko K, Sawada S, Yamada T, Ito A, Niizuma K, Tominaga T, Yamanaka A, Matsui K, Katagiri H. Optogenetic stimulation of vagal nerves for enhanced glucose-stimulated insulin secretion and β cell proliferation. Nat Biomed Eng. 2023; doi: 10.1038/s41551-023-01113-2. IF=29.234; CI=-
*Mukai Y, Okubo T, Lazarus M, Ono D, Tanaka KF, *Yamanaka A. Prostaglandin E2 induces long-lasting inhibition of noradrenergic neurons in the locus coeruleus and moderates the behavioral response to stressors. J Neurosci, 2023; 43 (47) 7982-7999; DOI: https://doi.org/10.1523/JNEUROSCI.0353-23.2023. IF=6.709; CI=-
Ito H, Fukatsu N, Rahman SM, Mukai Y, Izawa S, Ono D, Kilduff TS, *Yamanaka A. Deficiency of orexin signaling during sleep is involved in abnormal REM sleep architecture in narcolepsy. PNAS, 2023; 120 (41) e2301951120. https://doi.org/10.1073/pnas.2301951120. IF=12.779; CI=-
Li WR, Nakano T, Mizutani K, Matsubara T, Kawatani M, Mukai Y, Danjo T, Ito H, Aizawa H, Yamanaka A, Petersen CCH, Yoshimoto J, Yamashita T. Neural mechanisms underlying uninstructed orofacial movements during reward-based learning behaviors. Curr Biol, 2023; 33, 1-16. IF=10.834; CI=-
Herselman MF, Lin L, Luo S, Yamanaka A, Zhou XF, Bobrovskaya L. Sex-Dependent Effects of Chronic Restraint Stress on Mood-Related Behaviours and Neurochemistry in Mice. Int J Mol Sci, 2023; 24. IF=6.208 CI=-
Ono D, Wang H, Hung CJ, Wang HT, Kon N, Yamanaka A, Li Y, Sugiyama T. Network-driven intracellular cAMP coordinates circadian rhythm in the suprachiasmatic nucleus. Sci Adv, 2023 9:eabq7032. IF=14.136; CI=-
Sawamura T, Yuki N, Horii K, Naitou K, Yamaguchi H, Yamanaka A, Shiina T, Shimizu Y. Essential roles of the hypothalamic A11 region and the medullary raphe nuclei in regulation of colorectal motility in rats. Am J Physiol Gastrointest Liver Physiol, 2023; 324:G466-G475. IF=4.877; CI=-
Mukai Y, Li Y, Nakamura A, Fukatsu N, Iijima D, Abe M, Sakimura K, Itoi K, *Yamanaka A. Cre-dependent ACR2-expressing reporter mouse strain for efficient long-lasting inhibition of neuronal activity. Sci Rep. 2023 Mar 9;13(1):3966. doi: 10.1038/s41598-023-30907-2. IF=4.998; CI=-
2022
Tsuneki H, Maeda T, Takata S, Sugiyama M, Otsuka K, Ishizuka H, Onogi Y, Tokai E, Koshida C, Kon K, Takasaki I, Hamashima T, Sasahara M, Rudich A, Koya D, Sakurai T, Yanagisawa M, Yamanaka A, Wada T, Sasaoka T. Hypothalamic orexin prevents non-alcoholic steatohepatitis and hepatocellular carcinoma in obesity. Cell Rep, 2022; 41(3):111497. doi: 10.1016/j.celrep.2022.111497. IF=9.995; CI=-
Moriya S, Yamashita A, Masukawa D, Sakaguchi J, Ikoma Y, Sameshima Y, Kambe Y, Yamanaka A, Kuwaki T. Involvement of A5/A7 noradrenergic neurons and B2 serotonergic neurons in nociceptive processing: a fiber photometry study. Neural Regen Res, 2022; 17(4):881-886. doi: 10.4103/1673-5374.322465.
Zhou S, Yamashita A, Su J, Zhang Y, Wang W, Hao L, Yamanaka A, Kuwaki T. Activity of putative orexin neurons during cataplexy. Mol Brain, 2022; 15(1):21. doi: 10.1186/s13041-022-00907-w.
Amo R, Matias S, Yamanaka A, Tanaka KF, Uchida N, Watabe-Uchida M. A gradual temporal shift of dopamine responses mirrors the progression of temporal difference error in machine learning. Nat Neurosci, 2022; 25:1082-1092. IF=24.884; CI=-
Takahashi A, Durand-de Cuttoli R, Flanigan ME, Hasegawa E, Tsunematsu T, Aleyasin H, Cherasse Y, Miya K, Okada T, Keino-Masu K, Mitsui K, Li L, Patel V, Blitzer RD, Lazarus M, Tanaka KF, Yamanaka A, Sakurai T, Ogawa S, Russo SJ. Lateral habenula glutamatergic neurons projecting to the dorsal raphe nucleus promote aggressive arousal in mice. Nat Commun, 2022; 13:4039. IF=14.919; CI=-
Hung CJ, Yamanaka A, Ono D. Conditional knockout of Bmal1 in corticotropin-releasing factor neurons does not alter sleep-wake rhythm in mice. Front Neurosci, 2022; 15: 808754. doi: 10.3389/fnins.2021.808754. IF=4.677; CI=-
Niu M, Kasai A, Tanuma M, Seiriki K, Igarashi H, Kuwaki T, Nagayasu K, Miyaji K, Ueno H, Tanabe W, Seo K, Yokoyama R, Ohkubo J, Ago Y, Hayashida M, Inoue K, Takada M, Yamaguchi S, Nakazawa T, Kaneko S, Okuno H, Yamanaka A, Hashimoto H. Claustrum mediates bidirectional and reversible control of stress-induced anxiety responses. Sci Adv, 8(11):eabi6375. doi: 10.1126/sciadv.abi6375. IF=14.136; CI=-
Sato D, Hamada Y, Narita M, Mori T, Tezuka H, Suda Y, Tanaka K, Yoshida S, Tamura H, Yamanaka A, Senba E, Kuzumaki N, Narita M. Tumor suppression and improvement in immune systems by specific activation of dopamine D1-receptor-expressing neurons in the nucleus accmbens. Mol Brain, 15(1):17. doi: 10.1186/s13041-022-00902-1. IF=4.041; CI=-
Sun Y, Tisdale R, Park S, Ma SC, Heu J, Haire M, Allocca G, Yamanaka A, Morairty S, Kilduff T. The Development of Sleep/Wake Disruption and Cataplexy as Hypocretin/Orexin Neurons Degenerate in Male vs. Female Orexin/tTA; TetO-DTA Mice. Sleep, zsac039. doi: 10.1093/sleep/zsac039. IF=5.849; CI=-
Rahaman SM, Chowdhury S, Mukai Y, Ono D, Yamaguchi H, *Yamanaka A. Functional Interaction Between GABAergic Neurons in the Ventral Tegmental Area and Serotonergic Neurons in the Dorsal Raphe Nucleus. Front Neurosci. 2022;16:877054. doi: 10.3389/fnins.2022.877054. eCollection 2022. IF=5.152; CI=-
2021
Setsu T, Hamada Y, Oikawa D, Mori T, Ishiuji Y, Sato D, Narita M, Miyazaki S, Furuta E, Suda Y, Sakai H, Ochiya T, Tezuka H, Iseki M, Inada E, Yamanaka A, Kuzumaki N, Narita M. Direct evidence that the brain reward system is involved in the control of scratching behaviors induced by acute and chronic itch. Biochem Biophys Res Commun, 2021; 534:624-631. doi: 10.1016/j.bbrc.2020.11.030. IF=3.575; CI=0
Horii-Hayashi N, Nomoto K, Endo N, Yamanaka A, Kikusui T, Nishi M. Hypothalamic perifornical Urocortin-3 neurons modulate defensive responses to a potential threat stimulus. iScience, 2021; 24(1): 101908. doi: 10.1016/j.isci.2020.101908. IF=5.458; CI=0
Kato Y, Katsumata H, Inutsuka A, Yamanaka A, Onaka T, Minami S, Orikasa C. Involvement of MCH-oxytocin neural relay within the hypothalamus in murine nursing behavior. Sci Rep, 2021; 11(1): 3348. doi: 10.1038/s41598-021-82773-5. IF=4.379; CI=1
Lin YH, Yamahashi Y, Kuroda K, Faruk MO, Zhang X, Yamada K, Yamanaka A, Nagai T, Kaibuchi K. Accumbal D2R-medium spiny neurons regulate aversive behaviors through PKA-Rap1 pathway. Neurochem Int, 2021; 143: 104935. doi: 10.1016/j.neuint.2020.104935. IF=3.921; CI=2
Coffey AA, Joyal AA, Yamanaka A, Scammell TE. The impacts of age and sex in a mouse model of childhood narcolepsy. Front Neurosci, 2021; 15: 644757. doi: 10.3389/fnins.2021.644757. IF=4.677; CI=1
Izawa S*, Yoneshiro T, Kondoh K, Nakagiri S, Okamatsu-Ogura Y, Terao A, Minokoshi Y, Yamanaka A, Kimura K. Melanin-concentrating hormone-producing neurons in the hypothalamus regulate brown adipose tissue and thus contribute to energy expenditure. J Physiol, 2021: JP281241. doi: 10.1113/JP281241. IF=5.182; CI=1
Ohmura Y, Iwami K, Chowdhury S, Sasamori H, Sugiura C, Bouchekioua Y, Nishitani N, Yamanaka A, Yoshioka M. Disruption of model-based decision making by silencing of serotonin neurons in the dorsal raphe nucleus. Curr Biol, 2021; 31(11): 2446-2454. doi: 10.1016/j.cub.2021.03.048. IF=10.834; CI=1
Yamashita A, Moriya S, Nishi R, Kaminosono J, Yamanaka A, Kuwaki T*. Aversive emotion rapidly activates orexin neurons and increases heart rate in freely moving mice. Mol Brain, 2021; 14(1): 104. doi: 10.1186/s13041-021-00818-2. IF=4.041; CI=0
Matsubara T, Yanagida T, Kawaguchi N, Nakano T, Yoshimoto J, Sezaki M, Takizawa H, Tsunoda SP, Horigane SI, Ueda S, Takemoto-Kimura S, Kandori H, Yamanaka A, Yamashita T*. Remote control of neural function by X-ray-induced scintillation. Nat Commun, 2021; 12(1): 4478. doi: 10.1038/s41467-021-24717-1. IF=14.919; CI=3
Gao T, Li J, Watanabe Y, Hung C, Yamanaka A, Horie K, Yanagisawa M, Ohsawa M, Kume K. Gi-sleepnet: a highly versatile image-based sleep classification using a deep learning algorithm. Clocks & Sleep, 2021; 3(4): 581-597. doi: 10.3390/clockssleep3040041. IF=-; CI=-
Kawatani M, de Groat WC, Itoi K, Uchida K, Sakimura K, Yamanaka A, Yamashita T, Kawatani M. Downstream projection of Barrington’s nucleus to the spinal cord in mice. J Neurophysiol. 2021; 126(6): 1959-1977. doi: 10.1152/jn.00026.2021. IF=2.714; CI=-
Moriya R, Kanamaru M, Okuma N, Yoshikawa A, Tanaka KF, Hokari S, Ohshima Y, Yamanaka A, Honma M, Onimaru H, Kikuchi T, Izumizaki M. Optogenetic activation of DRN 5-HT neurons induced active wakefulness, not quiet wakefulness. Brain Res Bull 2021; 177: 129-142. doi: 10.1016/j.brainresbull.2021.09.019. IF=4.077; CI=-
2020
Zhang T, Yanagida J, Kamii H, Wada S, Domoto M, Sasase H, Deyama S, Takarada T, Hinoi E, Sakimura K, Yamanaka A, Maejima T, Mieda M, Sakurai T, Nishitani N, Nagayasu K, Kaneko S, Minami M, *Kaneda K. Glutamatergic neurons in the medial prefrontal cortex mediate the formation and retrieval of cocaine-associated memories in mice. Addict Biol, 2020; 25(1):e12723. doi: 10.1111/adb.12723. IF=4.28; CI=15
Wada S, Yanagida J, Sasase H, Zhang T, Li X, Kamii H, Domoto M, Deyama S, Hinoi E, Yamanaka A, Nishitani N, Nagayasu K, Kaneko S, Minami M, *Kaneda K. Acute restraint stress augments the rewarding memory of cocaine through activation of α1 adrenoceptors in the medial prefrontal cortex of mice. Neuropharmacol, 2020; 166:107968. doi: 10.1016/j.neuropharm.2020.107968. IF=5.25; CI=5
Moriya S, Yamanaka A, Masukawa D, Kambe Y, Sakaguchi J, Setoyama H, Yamanaka A, *Kuwaki T. Involvement of supralemniscal nucleus (B9) 5-HT neuronal system in nociceptive processing: a fiber photometry study. Mol Brain, 2020; 13(1):14. doi: 10.1186/s13041-020-0553-1. IF=4.041; CI=2
*Imayoshi I, Tabuchi S, Matsumoto M, Kitano S, Miyachi H, Kageyama R, Yamanaka A. Light-induced silencing of neural activity in Rosa26 knock-in and BAC transgenic mice conditionally expressing the microbial halorhodopsin eNpHR3. Sci Rep, 2020; 10(1):3191. doi: 10.1038/s41598-020-59984-3. IF=4.379; CI=1
Nagai Y, Takayama K, Nishitani N, Andoh C, Koda M, Shirakawa H, Nakagawa T, *Nagayasu K, Yamanaka A, *Kaneko S. The Role of Dorsal Raphe Serotonin Neurons in the Balance between Reward and Aversion. Int J Mol Sci, 2020; 21(6). pii: E2160. doi: 10.3390/ijms21062160. IF=5.923; CI=10
Hung CJ, Ono D, Kilduff TS, *Yamanaka A. Dual orexin and MCH neuron-ablated mice display severe sleep attacks and cataplexy. eLife, 2020; 9:e54275. doi: 10.7554/eLife.54275. IF=8.14; CI=5
Flanigan ME, Aleyasin H, Li L, Burnett CJ, Chan KL, LeClair KB, Lucas EK, Matikainen-Ankney B, Durand-de Cuttoli R, Takahashi A, Menard C, Pfau ML, Golden SA, Bouchard S, Calipari ES, Nestler EJ, DiLeone RJ, Yamanaka A, Huntley GW, Clem RL, *Russo SJ. Orexin signaling in GABAergic lateral habenula neurons modulates aggressive behavior in male mice. Nat Neurosci, 2020; 23(5): 638-650.doi: 10.1038/s41593-020-0617-7. IF=24.884; CI=22
*Moriya S, Yamashita A, Masukawa D, Setoyama H, Hwang Y, Yamanaka A, Kuwaki T. Involvement of A13 dopaminergic neurons located in the zona incerta in nociceptive processing: a fiber photometry study. Mol Brain, 2020; 13(1):60. doi: 10.1186/s13041-020-00600-w. IF=4.041; CI=1
*Abe C, Yamaoka Y, Maejima Y, Mikami T, Yokota S, Yamanaka A, *Morita H. VGLUT2-expressing neurons in the vestibular nuclear complex mediate gravitational stress-induced hypothermia in mice. Commun Biol, 2020; 3(1): 227. doi: 10.1038/s42003-020-0950-0. IF=6.268; CI=0
Yoshida K, Tsutsui-Kimura I, Kono A, Yamanaka A, Kobayashi K, Watanabe M, Mimura M, *Tanaka KF. Opposing ventral striatal medium spiny neuron activities are shaped by striatalparvalbumin-expressing interneurons during goal-directed behaviors. Cell Rep, 2020; 31(13):107829. doi: 10.1016/j.celrep.2020.107829. IF=9.423; CI=3
Kojima K, Miyoshi N, Shibukawa A, Chowdhury S, Tsujimura M, Noji T, Ishikita H, Yamanaka A, *Sudo Y. A Green-Sensitive, Long-Lived and Step-Functional Anion Channelrhodopsin-2 Variant as a High-Potential Neural Silencing Tool. J Phys Chem Lett, 2020; 11: 6214-6218. doi: 10.1021/acs.jpclett.0c01406. IF=6.475; CI=5
Mukai Y, Nagayama A, Itoi K, *Yamanaka A. Identification of substances which regulate activity of corticotropin-releasing factor-producing neurons in the paraventricular nucleus of the hypothalamus. Sci Rep, 2020; 10(1): 13639. doi: 10.1038/s41598-020-70481-5. IF=4.379; CI=1
*Ono D, Mukai Y, Hung CJ, Chowdhury S, Sugiyama T, *Yamanaka A. The mammalian circadian pacemaker regulates wakefulness via CRF neurons in the paraventricular nucleus of the hypothalamus. Sci Adv, 2020; 6(45): eabd0384. doi: 10.1126/sciadv.abd0384. IF=14.136; CI=7
Miyazaki K, Miyazaki KW, Sivori G, Yamanaka A, Tanaka KF, Doya K. Serotonergic projections to the orbitofrontal and medial prefrontal cortices differentially modulate waiting for future rewards. Sci Adv, 2020; 6(48): eabc7246. doi: 10.1126/sciadv.abc7246. IF=14.136; CI=6
2019
Macpherson T, Mizoguchi H, Yamanaka A, *Hikida T. Preproenkephalin-expressing ventral pallidal neurons control inhibitory avoidance learning. Neurochem Int, 2019; 126: 11-18. doi: 10.1016/j.neuint.2019.02.011. IF=3.921; CI=1
Liang L, Teh DBL, Dinh ND, Chen W, Chen Q, Wu Y, Chowdhury S, Yamanaka A, Sum TC, Chen CH, Thakor NV, All AH, *Liu X. Upconversion amplification through dielectric superlensing modulation. Nat Commun, 2019; 10: 1391. doi: 10.1038/s41467-019-09345-0. IF=14.919; CI=56
*Murata K, Kinoshita T, Fukazawa Y, Kobayashi K, Yamanaka A, Hikida T, Manabe H, Yamaguchi M. Opposing roles of dopamine receptor D1- and D2-expressing neurons in the anteromedial olfactory tubercle in acquisition of place preference in mice. Front Behav Neurosci, 2019; 13: 50. doi: 10.3389/fnbeh.2019.00050. IF=3.558; CI=6
Yamanashi T, Maki M, Kojima K, Shibukawa A, Tsukamoto T, Chowdhury S, Yamanaka A, Takagi S, *Sudo Y. Quantitation of the neural silencing activity of anion channelrhodopsins in Caenorhabditis elegans and their applicability for long-term illumination. Sci Rep, 2019; 9: 7863. doi: 10.1038/s41598-019-44308-x. IF=4.379; CI=4
Chowdhury S, Hung CJ, Izawa S, Inutsuka A, Kawamura M, Kawashima T, Bito H, Imayoshi I, Abe M, Sakimura K, *Yamanaka A. Dissociating orexin-dependent and -independent functions of orexin neurons using novel Orexin-Flp knock-in mice. eLife, 2019; 8: e44927. doi: 10.7554/eLife.44927. IF=8.14; CI=7
Chowdhury S, Matsubara T, Miyazaki T, Ono D, Fukatsu N, Abe M, Sakimura K, Sudo Y, *Yamanaka A. GABA neurons in the ventral tegmental area regulate non-rapid eye movement sleep in mice. eLife, 2019; 8: e44928. doi: 10.7554/eLife.44928. IF=8.14; CI=21
Moriya S, Yamashita A, Nishi R, Ikoma Y, Yamanaka A, *Kuwaki T. Acute nociceptive stimuli rapidly induce the activity of serotonin and noradrenalin neurons in the brain stem of awake mice. IBRO Rep, 2019; 7: 1-9. doi: 10.1016/j.ibror.2019.05.005. IF=2.404; CI=6
Nishitani N, *Ohmura Y, Nagayasu K, Shibui N, Kaneko S, Ohashi A, Yoshida T, Yamanaka A, Yoshioka M. CRISPR/Cas9-mediated in vivo gene editing reveals that neuronal 5-HT1A receptors in the dorsal raphe nucleus contribute to body temperature regulation in mice. Brain Res, 2019; 1719: 243-252. doi: 10.1016/j.brainres.2019.06.009. IF=3.252; CI=2
Sugiyama E, Kondo T, Kuzumaki N, Honda K, Yamanaka A, Narita M, Suematsu M, *Sugiura Y. Mechanical allodynia induced by optogenetic sensory nerve excitation activates dopamine signaling and metabolism in medial nucleus accumbens. Neurochem Int, 2019; 129:104494. doi: 10.1016/j.neuint.2019.104494. IF=3.921; CI=5
*Ono D, Honma K-i, Yanagawa Y, Yamanaka A, Honma S. GABA in the suprachiasmatic nucleus refines circadian output rhythms in mice. Commun Biol, 2019; 2: 232. doi: 10.1038/s42003-019-0483-6. IF=6.268; CI=17
Matsubara T, Hayashi K, Wakatsuki K, Abe M, Ozaki N, Yamanaka A, Mizumura K, *Taguchi T. Thin-fibre receptors expressing acid-sensing ion channel 3 contribute to muscular mechanical hypersensitivity after exercise. Eur J Pain, 2019; 23:1801-1813. doi: 10.1002/ejp.1454 IF=3.931; CI=24
Izawa S, Chowdhury S, Miyazaki T, Mukai Y, Ono D, Inoue R, Ohmura Y, Mizoguchi H, Kimura K, Yoshioka M, Terao A, Kilduff TS, *Yamanaka A. REM sleep–active MCH neurons are involved in forgetting hippocampus-dependent memories. Science, 2019; 365: 1308-1313. doi: 10.1126/science.aax9238. IF=47.728; CI=49
Williams R, Tsunematsu T, Thomas A, Bogyo K, *Yamanaka A, *Kilduff TS. Transgenic archaerhodopsin-3 expression in hypocretin/orexin neurons engenders cellular dysfunction and features of type 2 narcolepsy. J Neurosci, 2019; 20:39(47):9435-9452. doi: 10.1523/JNEUROSCI.0311-19.2019. IF=6.167; CI=6
Ohmura Y, Tsutsui-Kimura I, Sasamori H, Nebuka M, Nishitani N, Tanaka KF, Yamanaka A, Yoshioka M. Different roles of distinct serotonergic pathways in anxiety-like behavior, antidepressant-like, and anti-impulsive effects. Neuropharmacol, 2020; 107703. doi: 10.1016/j.neuropharm.2019.107703. IF=5.25; CI=21
2018
Matsui S, *Sasaki T, Kohno D, Yaku K, Inutsuka A, Yokota-Hashimoto H, Kikuchi O, Suga T, Kobayashi M, Yamanaka A, Harada A, Nakagawa T, Onaka T, Kitamura T. Neuronal SIRT1 regulates macronutrient-based diet selection through FGF21 and oxytocin signaling in mice. Nat Commun, 2018; 9: 4604. doi: 10.1038/s41467-018-07033-z. IF=14.919; CI=27
Kondo T, Saito R, Otaka M, Yoshino-Saito K, Yamanaka A, Yamamori T, Watakabe A, Mizukami H, Schnitzer MJ, Tanaka KF, Ushiba J, *Okano H. Calcium transient dynamics of neural ensembles in the primary motor cortex of naturally behaving monkeys. Cell Rep, 2018; 24: 2191-2195.e2194. doi: 10.1016/j.celrep.2018.07.057. IF=9.423; CI=22
Heiss JE, Yamanaka A, *Kilduff TS. Parallel arousal pathways in the lateral hypothalamus. eNeuro, 2018; 5. doi: 10.1523/ENEURO.0228-18.2018. IF=4.081; CI=9
Ikoma Y, Kusumoto-Yoshida I, Yamanaka A, Ootsuka Y, *Kuwaki T. Inactivation of serotonergic neurons in the rostral medullary raphe attenuates stress-induced tachypnea and tachycardia in mice. Front Physiol, 2018; 9: 832. doi: 10.3389/fphys.2018.00832. IF=4.566; CI=8
Koizumi K, Inoue M, Chowdhury S, Bito H, Yamanaka A, Ishizuka T, *Yawo H. Functional emergence of a column-like architecture in layer 5 of mouse somatosensory cortex in vivo. J Physiol Sci, 2018; 69:65-77. doi: 10.1007/s12576-018-0618-4. IF=2.781; CI=2
Miyazaki K, Miyazaki KW, Yamanaka A, Tokuda T, Tanaka KF, *Doya K. Reward probability and timing uncertainty alter the effect of dorsal raphe serotonin neurons on patience. Nat Commun, 2018; 9: 2048. doi: 10.1038/s41467-018-04496-y. IF=14.919; CI=24
*Black SW, Sun JD, Santiago P, Laihsu A, Kimura N, Yamanaka A, Bersot R, Humphries PS. Partial ablation of the orexin field induces a sub-narcoleptic phenotype in a conditional mouse model of orexin neurodegeneration. Sleep, 2018; 41: zsy116. doi: 10.1093/sleep/zsy116. IF=5.849; CI=3
Thannickal TC, John J, Shan L, Swaab DF, Wu MF, Ramanathan L, McGregor R, Chew KT, Cornford M, Yamanaka A, Inutsuka A, Fronczek R, Lammers GJ, Worley PF, *Siegel JM. Opiates increase the number of hypocretin-producing cells in human and mouse brain and reverse cataplexy in a mouse model of narcolepsy. Sci Transl Med, 2018; 10. doi: 10.1126/scitranslmed.aao4953. IF=17.956; CI=36
Moriya S, Yamashita A, Kawashima S, Nishi R, Yamanaka A, *Kuwaki T. Acute aversive stimuli rapidly increase the activity of ventral tegmental area dopamine neurons in awake mice. Neuroscience, 2018; 386: 16-23. doi: 10.1016/j.neuroscience.2018.06.027. IF=3.59; CI=18
*Hashimoto M, Yamanaka A, Kato S, Tanifuji M, Kobayashi K, Yaginuma H. Anatomical evidence for a direct projection from purkinje cells in the mouse cerebellar vermis to medial parabrachial nucleus. Front Neural Circuits, 2018; 12: 6. doi: 10.3389/fncir.2018.00006. IF=3.492; CI=9
*Kikusui T, Kajita M, Otsuka N, Hattori T, Kumazawa K, Watarai A, Nagasawa M, Inutsuka A, Yamanaka A, Matsuo N, Covington HE, 3rd, Mogi K. Sex differences in olfactory-induced neural activation of the amygdala. Behav Brain Res, 2018; 346: 96-104. doi: 10.1016/j.bbr.2017.11.034. IF=3.332; CI=6
Nasanbuyan N, Yoshida M, Takayanagi Y, Inutsuka A, Nishimori K, Yamanaka A, *Onaka T. Oxytocin-oxytocin receptor systems facilitate social defeat posture in male mice. Endocrinol, 2018; 159: 763-775.doi: 10.1210/en.2017-00606. IF=4.736; CI=25
Watanabe M, Sugiura Y, Sugiyama E, Narita M, Navratilova E, Kondo T, Uchiyama N, Yamanaka A, Kuzumaki N, Porreca F, *Narita M. Extracellular N-acetylaspartylglutamate released in the nucleus accumbens modulates the pain sensation: Analysis using a microdialysis/mass spectrometry integrated system. Mol Pain, 2018; 14: 1744806918754934. doi: 10.1177/1744806918754934. IF=3.395; CI=7
Watanabe M, Narita M, Hamada Y, Yamashita A, Tamura H, Ikegami D, Kondo T, Shinzato T, Shimizu T, Fukuchi Y, Muto A, Okano H, Yamanaka A, Tawfik VL, Kuzumaki N, Navratilova E, Porreca F, *Narita M. Activation of ventral tegmental area dopaminergic neurons reverses pathological allodynia resulting from nerve injury or bone cancer. Mol Pain, 2018; 14: 1744806918756406. doi: 10.1177/1744806918756406. IF=3.395; CI=27
Suda Y, Kuzumaki N, Narita M, Hamada Y, Shibasaki M, Tanaka K, Tamura H, Kawamura T, Kondo T, Yamanaka A, *Narita M. Effect of ghrelin on the motor deficit caused by the ablation of nigrostriatal dopaminergic cells or the inhibition of striatal dopamine receptors. Biochem Biophys Res Commun, 2018; 496: 1102-1108. doi: 10.1016/j.bbrc.2018.01.145. IF=3.575; CI=5
Futatsuki T, Yamashita A, Ikbar KN, Yamanaka A, Arita K, Kakihana Y, *Kuwaki T. Involvement of orexin neurons in fasting- and central adenosine-induced hypothermia. Sci Rep, 2018; 8: 2717. doi: 10.1038/s41598-018-21252-w. IF=4.379; CI=14
2017
*Dergacheva O, Yamanaka A, Schwartz AR, Polotsky VY, Mendelowitz D. Optogenetic identification of hypothalamic orexin neuron projections to paraventricular spinally projecting neurons. Am J Physiol Heart Circ Physiol, 2017; 312: 808-817. doi: 10.1152/ajpheart.00572.2016. IF=4.733; CI=15
Hayashi K, Katanosaka K, Abe M, Yamanaka A, Nosaka K, Mizumura K, *Taguchi T. Muscular mechanical hyperalgesia after lengthening contractions in rats depends on stretch velocity and range of motion. Eur J Pain, 2017; 21: 125-139. doi: 10.1002/ejp.909. IF=3.931; CI=10
2016
Wakaizumi K, Kondo T, Hamada Y, Narita M, Kawabe R, Narita H, Watanabe M, Kato S, Senba E, Kobayashi K, Kuzumaki N, Yamanaka A, Morisaki H, *Narita M. Involvement of mesolimbic dopaminergic network in neuropathic pain relief by treadmill exercise: A study for specific neural control with Gi-DREADD in mice. Mol Pain, 2016; 12: 1744806916681567. doi: 10.1177/1744806916681567. IF=3.395; CI=22
Miyamoto D, Hirai D, Fung CC, Inutsuka A, Odagawa M, Suzuki T, Boehringer R, Adaikkan C, Matsubara C, Matsuki N, Fukai T, McHugh TJ, Yamanaka A, *Murayama M. Top-down cortical input during NREM sleep consolidates perceptual memory. Science, 2016; 352: 1315-1318. doi: 10.1126/science.aaf0902. IF=47.728; CI=66
Inutsuka A, Yamashita A, Chowdhury S, Nakai J, Ohkura M, Taguchi T, *Yamanaka A. The integrative role of orexin/hypocretin neurons in nociceptive perception and analgesic regulation. Sci Rep, 2016; 6: 29480. doi: 10.1038/srep29480. IF=4.379; CI=61
Chowdhury S, *Yamanaka A. Optogenetic activation of serotonergic terminals facilitates GABAergic inhibitory input to orexin/hypocretin neurons. Sci Rep, 2016; 6: 36039. doi: 10.1038/srep36039. IF=4.379; CI=20
*Dergacheva O, Yamanaka A, Schwartz AR, Polotsky VY, Mendelowitz D. Hypoxia and hypercapnia inhibit hypothalamic orexin neurons in rats. J Neurophysiol, 2016; 116: 2250-2259. doi: 10.1152/jn.00196.2016. IF=2.714; CI=13
*Dergacheva O, Yamanaka A, Schwartz AR, Polotsky VY, Mendelowitz D. Direct projections from hypothalamic orexin neurons to brainstem cardiac vagal neurons. Neuroscience, 2016; 339: 47-53. doi: 10.1016/j.neuroscience.2016.09.038. IF=3.59; CI=14
Branch AF, Navidi W, Tabuchi S, Terao A, Yamanaka A, *Scammell TE, Diniz Behn C. Progressive loss of the orexin neurons reveals dual effects on wakefulness. Sleep, 2016; 39: 369-377. doi: 10.5665/sleep.5446. IF=5.849; CI=29
2015
Hososhima S, Yuasa H, Ishizuka T, Hoque MR, Yamashita T, Yamanaka A, Sugano E, Tomita H, *Yawo H. Near-infrared (NIR) up-conversion optogenetics. Sci Rep, 2015; 5: 16533. doi: 10.1038/srep16533. IF=4.379; CI=59
Ishii K, Kubo K, Endo T, Yoshida K, Benner S, Ito Y, Aizawa H, Aramaki M, Yamanaka A, Tanaka K, Takata N, Tanaka KF, Mimura M, Tohyama C, Kakeyama M, *Nakajima K. Neuronal Heterotopias Affect the Activities of Distant Brain Areas and Lead to Behavioral Deficits. J Neurosci, 2015; 35: 12432-12445. doi: 10.1523/JNEUROSCI.3648-14.2015. IF=6.167; CI=23
*Mizoguchi H, Katahira K, Inutsuka A, Fukumoto K, Nakamura A, Wang T, Nagai T, Sato J, Sawada M, Ohira H, Yamanaka A, Yamada K. Insular neural system controls decision-making in healthy and methamphetamine-treated rats. Proc Natl Acad Sci U S A, 2015; 112: E3930-3939. doi: 10.1073/pnas.1418014112. IF=11.205; CI=30
*Shibasaki K, Sugio S, Takao K, Yamanaka A, Miyakawa T, Tominaga M, Ishizaki Y. TRPV4 activation at the physiological temperature is a critical determinant of neuronal excitability and behavior. Pflugers Arch, 2015; 467: 2495-2507. doi: 10.1007/s00424-015-1726-0. IF=3.657; CI=42
Kato HE, Kamiya M, Sugo S, Ito J, Taniguchi R, Orito A, Hirata K, Inutsuka A, Yamanaka A, Maturana AD, Ishitani R, Sudo Y, Hayashi S, *Nureki O. Atomistic design of microbial opsin-based blue-shifted optogenetics tools. Nat Commun, 2015; 6: 7177. doi: 10.1038/ncomms8177. IF=14.919; CI=44
Manita S, Suzuki T, Homma C, Matsumoto T, Odagawa M, Yamada K, Ota K, Matsubara C, Inutsuka A, Sato M, Ohkura M, Yamanaka A, Yanagawa Y, Nakai J, Hayashi Y, Larkum ME, *Murayama M. A Top-Down Cortical Circuit for Accurate Sensory Perception. Neuron, 2015; 86: 1304-1316. doi: 10.1016/j.neuron.2015.05.006. IF=17.173; CI=173
*Taguchi T, Katanosaka K, Yasui M, Hayashi K, Yamashita M, Wakatsuki K, Kiyama H, Yamanaka A, Mizumura K. Peripheral and spinal mechanisms of nociception in a rat reserpine-induced pain model. Pain, 2015; 156: 415-427. doi: 10.1097/01.j.pain.0000460334.49525.5e. IF=6.961; CI=39
2014
Miyazaki KW, Miyazaki K, Tanaka KF, Yamanaka A, Takahashi A, Tabuchi S, *Doya K. Optogenetic activation of dorsal raphe serotonin neurons enhances patience for future rewards. Curr Biol, 2014; 24: 2033-2040. doi: 10.1016/j.cub.2014.07.041. IF=10.834; CI=139
Inutsuka A, Inui A, Tabuchi S, Tsunematsu T, Lazarus M, *Yamanaka A. Concurrent and robust regulation of feeding behaviors and metabolism by orexin neurons. Neuropharmacol, 2014; 85: 451-460. doi: 10.1016/j.neuropharm.2014.06.015. IF=5.25; CI=65
Beppu K, Sasaki T, Tanaka KF, Yamanaka A, Fukazawa Y, Shigemoto R, *Matsui K. Optogenetic countering of glial acidosis suppresses glial glutamate release and ischemic brain damage. Neuron, 2014; 81: 314-320. doi: 10.1016/j.neuron.2013.11.011. IF=17.173; CI=117
Takayama Y, Shibasaki K, Suzuki Y, Yamanaka A, *Tominaga M. Modulation of water efflux through functional interaction between TRPV4 and TMEM16A/anoctamin 1. FASEB J, 2014; 28: 2238-2248. doi: 10.1096/fj.13-243436. IF=5.191; CI=53
Black SW, Morairty SR, Chen TM, Leung AK, Wisor JP, *Yamanaka A, *Kilduff TS. GABAB agonism promotes sleep and reduces cataplexy in murine narcolepsy. J Neurosci, 2014; 34: 6485-6494. doi: 10.1523/JNEUROSCI.0080-14.2014. IF=6.167; CI=45
Tabuchi S, Tsunematsu T, Black SW, Tominaga M, Maruyama M, Takagi K, Minokoshi Y, Sakurai T, Kilduff TS, *Yamanaka A. Conditional ablation of orexin/hypocretin neurons: a new mouse model for the study of narcolepsy and orexin system function. J Neurosci, 2014; 34: 6495-6509. doi: 10.1523/JNEUROSCI.0073-14.2014. IF=6.167; CI=114
Tsunematsu T, Ueno T, Tabuchi S, Inutsuka A, Tanaka KF, Hasuwa H, Kilduff TS, Terao A, *Yamanaka A. Optogenetic manipulation of activity and temporally controlled cell-specific ablation reveal a role for MCH neurons in sleep/wake regulation. J Neurosci, 2014; 34: 6896-6909. doi: 10.1523/JNEUROSCI.5344-13.2014. IF=6.167; CI=124
*Ohmura Y, Tanaka KF, Tsunematsu T, *Yamanaka A, Yoshioka M. Optogenetic activation of serotonergic neurons enhances anxiety-like behaviour in mice. Int J Neuropsychopharmacol, 2014; 17:1777-1783. doi: 10.1017/S1461145714000637. IF=5.176; CI=60
2013
Tsunematsu T, Tanaka KF, Yamanaka A, *Koizumi A. Ectopic expression of melanopsin in orexin/hypocretin neurons enables control of wakefulness of mice in vivo by blue light. Neurosci Res, 2013; 75: 23-28. doi: 10.1016/j.neures.2012.07.005. IF=3.304; CI=27
Tsunematsu T, Tabuchi S, Tanaka KF, Boyden ES, Tominaga M, *Yamanaka A. Long-lasting silencing of orexin/hypocretin neurons using archaerhodopsin induces slow-wave sleep in mice. Behav Brain Res, 2013; 255: 64-74. doi: 10.1016/j.bbr.2013.05.021. IF=3.332; CI=72
*Taguchi T, Yasui M, Kubo A, Abe M, Kiyama H, Yamanaka A, Mizumura K. Nociception originating from the crural fascia in rats. Pain, 2013; 154: 1103-1114. doi: 10.1016/j.pain.2013.03.017. IF=6.961; CI=30
John J, Thannickal TC, McGregor R, Ramanathan L, Ohtsu H, Nishino S, Sakai N, Yamanaka A, Stone C, Cornford M, *Siegel JM. Greatly increased numbers of histamine cells in human narcolepsy with cataplexy. Ann Neurol, 2013; 74: 786-793. doi: 10.1002/ana.23968. IF=10.422; CI=63
Tsujino N, Tsunematsu T, Uchigashima M, Konno K, Yamanaka A, Kobayashi K, Watanabe M, Koyama Y, *Sakurai T. Chronic alterations in monoaminergic cells in the locus coeruleus in orexin neuron-ablated narcoleptic mice. PLoS One, 2013; 8: e70012. doi: 10.1371/journal.pone.0070012. IF=3.24; CI=13
Tabuchi S, Tsunematsu T, Kilduff TS, Sugio S, Xu M, Tanaka KF, Takahashi S, Tominaga M, *Yamanaka A. Influence of inhibitory serotonergic inputs to orexin/hypocretin neurons on the diurnal rhythm of sleep and wakefulness. Sleep, 2013; 36: 1391-1404. doi: 10.5665/sleep.2972. IF=5.849; CI=29
2012
*Tanaka KF, Matsui K, Sasaki T, Sano H, Sugio S, Fan K, Hen R, Nakai J, Yanagawa Y, Hasuwa H, Okabe M, Deisseroth K, Ikenaka K, Yamanaka A. Expanding the repertoire of optogenetically targeted cells with an enhanced gene expression system. Cell Rep, 2012; 2: 397-406. doi: 10.1016/j.celrep.2012.06.011. IF=9.423; CI=101
*Imayoshi I, Tabuchi S, Hirano K, Sakamoto M, Kitano S, Miyachi H, Yamanaka A, Kageyama R. Light-induced silencing of neural activity in Rosa26 knock-in mice conditionally expressing the microbial halorhodopsin eNpHR2.0. Neurosci Res, 2013; 75: 53-58. doi: 10.1016/j.neures.2012.03.008. IF=3.304; CI=6
2011
Hirashima N, Tsunematsu T, Ichiki K, Tanaka H, Kilduff TS, *Yamanaka A. Neuropeptide B induces slow wave sleep in mice. Sleep, 2011; 34: 31-37. doi: 10.1093/sleep/34.1.31. IF=5.849; CI=9
Tsunematsu T, Kilduff TS, Boyden ES, Takahashi S, Tominaga M, *Yamanaka A. Acute optogenetic silencing of orexin/hypocretin neurons induces slow-wave sleep in mice. J Neurosci, 2011; 31: 10529-10539. doi: 10.1523/JNEUROSCI.0784-11.2011. IF=6.167; CI=154
Before 2010
Kawaguchi H, Yamanaka A, Uchida K, Shibasaki K, Sokabe T, Maruyama Y, Yanagawa Y, Murakami S, *Tominaga M. Activation of polycystic kidney disease-2-like 1 (PKD2L1)-PKD1L3 complex by acid in mouse taste cells. J Biol Chem, 2010; 285: 17277-17281. doi: 10.1074/jbc.C110.132944. IF=5.157; CI=38
Mihara H, Boudaka A, Shibasaki K, Yamanaka A, Sugiyama T, *Tominaga M. Involvement of TRPV2 activation in intestinal movement through nitric oxide production in mice. J Neurosci, 2010; 30: 16536-16544. doi: 10.1523/JNEUROSCI.4426-10.2010. IF=6.167; CI=56
*Yamanaka A, Tabuchi S, Tsunematsu T, Fukazawa Y, Tominaga M. Orexin directly excites orexin neurons through orexin 2 receptor. J Neurosci, 2010; 30: 12642-12652. doi: 10.1523/JNEUROSCI.2120-10.2010. IF=6.167; CI=73
Xie X, Wisor JP, Hara J, Crowder TL, LeWinter R, Khroyan TV, Yamanaka A, Diano S, Horvath TL, Sakurai T, Toll L, *Kilduff TS. Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia. J Clin Invest, 2008; 118: 2471-2481. doi: 10.1113/jphysiol.2006.108266. IF=14.808; CI=73
Tsunematsu T, Fu LY, *Yamanaka A, Ichiki K, Tanoue A, Sakurai T, van den Pol AN. Vasopressin increases locomotion through a V1a receptor in orexin/hypocretin neurons: implications for water homeostasis. J Neurosci, 2008; 28: 228-238. doi: 10.1523/JNEUROSCI.3490-07.2008. IF=6.167; CI=53
Xie X, Crowder TL, Yamanaka A, Morairty SR, Lewinter RD, Sakurai T, *Kilduff TS. GABA(B) receptor-mediated modulation of hypocretin/orexin neurones in mouse hypothalamus. J Physiol, 2006; 574: 399-414. doi: 10.1113/jphysiol.2006.108266. IF=5.182; CI=74
*Yamanaka A, Muraki Y, Ichiki K, Tsujino N, Kilduff TS, Goto K, Sakurai T. Orexin neurons are directly and indirectly regulated by catecholamines in a complex manner. J Neurophysiol, 2006; 96: 284-298. doi: 10.1152/jn.01361.2005. IF=2.714; CI=95
Toshinai K, Yamaguchi H, Sun Y, Smith RG, Yamanaka A, Sakurai T, Date Y, Mondal MS, Shimbara T, Kawagoe T, Murakami N, Miyazato M, Kangawa K, *Nakazato M. Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor. Endocrinol, 2006; 147: 2306-2314. doi: 10.1210/en.2005-1357. IF=4.736; CI=282
Takayasu S, Sakurai T, Iwasaki S, Teranishi H, Yamanaka A, Williams SC, Iguchi H, Kawasawa YI, Ikeda Y, Sakakibara I, Ohno K, Ioka RX, Murakami S, Dohmae N, Xie J, Suda T, Motoike T, Ohuchi T, Yanagisawa M, *Sakai J. A neuropeptide ligand of the G protein-coupled receptor GPR103 regulates feeding, behavioral arousal, and blood pressure in mice. Proc Natl Acad Sci U S A, 2006; 103: 7438-7443. doi: 10.1073/pnas.0602371103. IF=11.205; CI=133
*Obara K, Uchino M, Koide M, Yamanaka A, Nakayama K. Stretch-induced triphosphorylation of myosin light chain and myogenic tone in canine basilar artery. Eur J Pharmacol, 2006; 534: 141-151. doi: 10.1016/j.ejphar.2005.12.086. IF=4.432; CI=7
Tsujino N, *Yamanaka A, Ichiki K, Muraki Y, Kilduff TS, Yagami K, Takahashi S, Goto K, Sakurai T. Cholecystokinin activates orexin/hypocretin neurons through the cholecystokinin A receptor. J Neurosci, 2005; 25: 7459-7469. doi: 10.1523/JNEUROSCI.1193-05.2005. IF=6.167; CI=107
*Sakurai T, Nagata R, Yamanaka A, Kawamura H, Tsujino N, Muraki Y, Kageyama H, Kunita S, Takahashi S, Goto K, Koyama Y, Shioda S, Yanagisawa M. Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice. Neuron, 2005; 46: 297-308. doi: 10.1016/j.neuron.2005.03.010. IF=17.173; CI=353
Winsky-Sommerer R, Yamanaka A, Diano S, Borok E, Roberts AJ, Sakurai T, Kilduff TS, Horvath TL, *de Lecea L. Interaction between the corticotropin-releasing factor system and hypocretins (orexins): a novel circuit mediating stress response. J Neurosci, 2004; 24: 11439-11448. doi: 10.1523/JNEUROSCI.3459-04.2004. IF=6.167; CI=321
Muraki Y, *Yamanaka A, Tsujino N, Kilduff TS, Goto K, Sakurai T. Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor. J Neurosci, 2004; 24: 7159-7166. doi: 10.1523/JNEUROSCI.1027-04.2004. IF=6.167; CI=144
Muroya S, Funahashi H, Yamanaka A, Kohno D, Uramura K, Nambu T, Shibahara M, Kuramochi M, Takigawa M, Yanagisawa M, Sakurai T, Shioda S, *Yada T. Orexins (hypocretins) directly interact with neuropeptide Y, POMC and glucose-responsive neurons to regulate Ca 2+ signaling in a reciprocal manner to leptin: orexigenic neuronal pathways in the mediobasal hypothalamus. Eur J Neurosci, 2004; 19: 1524-1534. doi: 10.1111/j.1460-9568.2004.03255.x. IF=3.386; CI=194
Zhu Y, Miwa Y, Yamanaka A, Yada T, Shibahara M, Abe Y, *Sakurai T, Goto K. Orexin receptor type-1 couples exclusively to pertussis toxin-insensitive G-proteins, while orexin receptor type-2 couples to both pertussis toxin-sensitive and -insensitive G-proteins. J Pharmacol Sci, 2003; 92: 259-266. IF=3.337; CI=131
Yamanaka A, Beuckmann CT, Willie JT, Hara J, Tsujino N, Mieda M, Tominaga M, Yagami K, Sugiyama F, Goto K, Yanagisawa M, *Sakurai T. Hypothalamic orexin neurons regulate arousal according to energy balance in mice. Neuron, 2003; 38: 701-713. doi: 10.1016/S0896-6273(03)00331-3. IF=17.173; CI=647
Tanaka H, Yoshida T, Miyamoto N, Motoike T, Kurosu H, Shibata K, Yamanaka A, Williams SC, Richardson JA, Tsujino N, Garry MG, Lerner MR, King DS, O'Dowd BF, Sakurai T, *Yanagisawa M. Characterization of a family of endogenous neuropeptide ligands for the G protein-coupled receptors GPR7 and GPR8. Proc Natl Acad Sci U S A, 2003; 100: 6251-6256. doi: 10.1073/pnas.0837789100. IF=11.205; CI=152
Yamanaka A, Muraki Y, Tsujino N, Goto K, *Sakurai T. Regulation of orexin neurons by the monoaminergic and cholinergic systems. Biochem Biophys Res Commun, 2003; 303: 120-129. doi:10.1016/S0006-291X(03)00299-7. IF=3.575; CI=172
Zhu Y, Yamanaka A, Kunii K, Tsujino N, Goto K, *Sakurai T. Orexin-mediated feeding behavior involves both leptin-sensitive and -insensitive pathways. Physiol Behav, 2002; 77: 251-257. doi: 10.1016/S0031-9384(02)00843-0. IF=3.244; CI=131
Nanmoku T, Isobe K, Sakurai T, Yamanaka A, Takekoshi K, Kawakami Y, Goto K, *Nakai T. Effects of orexin on cultured porcine adrenal medullary and cortex cells. Regul Pept, 2002; 104: 125-130. doi: 10.1016/s0167-0115(01)00356-1. IF=1.813; CI=41
Yamanaka A, Tsujino N, Funahashi H, Honda K, Guan JL, Wang QP, Tominaga M, Goto K, Shioda S, *Sakurai T. Orexins activate histaminergic neurons via the orexin 2 receptor. Biochem Biophys Res Commun, 2002; 290: 1237-1245. doi: 10.1006/bbrc.2001.6318. IF=3.575; CI=220
Obara K, Saito M, Yamanaka A, Uchino M, *Nakayama K. Involvement of different activator Ca2+ in the rate-dependent stretch-induced contractions of canine basilar artery. Jpn J Physiol, 2001; 51: 327-335. doi: 10.2170/jjphysiol.51.327. IF=2.781; CI=13
Yamada M, Miyakawa T, Duttaroy A, Yamanaka A, Moriguchi T, Makita R, Ogawa M, Chou CJ, Xia B, Crawley JN, Felder CC, Deng CX, *Wess J. Mice lacking the M3 muscarinic acetylcholine receptor are hypophagic and lean. Nature, 2001; 410: 207-212. doi: 10.1038/35065604. IF=49.962; CI=298
Nanmoku T, Isobe K, Sakurai T, Yamanaka A, Takekoshi K, Kawakami Y, Ishii K, Goto K, *Nakai T. Orexins suppress catecholamine synthesis and secretion in cultured PC12 cells. Biochem Biophys Res Commun, 2000; 274: 310-315. doi: 10.1006/bbrc.2000.3137. IF=3.575; CI=44
Abe Y, Nakayama K, Yamanaka A, Sakurai T, *Goto K. Subtype-specific trafficking of endothelin receptors. J Biol Chem, 2000; 275: 8664-8671. doi: 10.1074/jbc.275.12.8664. IF=5.157; CI=49
Yamanaka A, Kunii K, Nambu T, Tsujino N, Sakai A, Matsuzaki I, Miwa Y, Goto K, *Sakurai T. Orexin-induced food intake involves neuropeptide Y pathway. Brain Res, 2000; 859: 404-409. doi: 10.1016/S0006-8993(00)02043-6. IF=3.252; CI=196
Yamanaka A, *Sakurai T, Katsumoto T, Yanagisawa M, Goto K. Chronic intracerebroventricular administration of orexin-A to rats increases food intake in daytime, but has no effect on body weight. Brain Res, 1999; 849: 248-252. doi: 10.1016/S0006-8993(99)01905-8. IF=3.252; CI=172
Kunii K, Yamanaka A, Nambu T, Matsuzaki I, Goto K, *Sakurai T. Orexins/hypocretins regulate drinking behaviour. Brain Res, 1999; 842: 256-261. doi: 10.1016/S0006-8993(99)01884-3. IF=3.252; CI=173
Yamanaka A, *Ishikawa T, Goto K. Characterization of endothelium-dependent relaxation independent of NO and prostaglandins in guinea pig coronary artery. J Pharmacol Exp Ther, 1998; 285: 480-489. IF=4.03; CI=46
Yamada M, Ishikawa T, Yamanaka A, Fujimori A, *Goto K. Local neurogenic regulation of rat hindlimb circulation: CO2-induced release of calcitonin gene-related peptide from sensory nerves. Br J Pharmacol, 1997; 122: 710-714. doi: 10.1038/sj.bjp.0701423 16322150. IF=8.739; CI=11
Review paper:
1. *Yamanaka A, Tsunematsu T. New approaches for the study of orexin function. J Neuroendocrinol, 2010; 22: 818-824. doi: 10.1111/j.1365-2826.2010.02015.x IF=3.627; CI=10
2. *Koizumi A, Tanaka KF, Yamanaka A. The manipulation of neural and cellular activities by ectopic expression of melanopsin. Neurosci Res, 2012; 75: 3-5. doi: 10.1016/j.neures.2012.07.010 IF=3.304; CI=23
3. Tsunematsu T, *Yamanaka A. The role of orexin/hypocretin in the central nervous system and peripheral tissues. Vitam Horm, 2012; 89:19-33. doi: 10.1016/B978-0-12-394623-2.00002-0 IF=3.421; CI=29
4. Inutsuka A, *Yamanaka A. The physiological role of orexin/hypocretin neurons in the regulation of sleep/wakefulness and neuroendocrine functions. Front Endocrinol, 2013; 6;4:18. doi: 10.3389/fendo.2013.00018 IF=5.555; CI=118
5. Inutsuka A, *Yamanaka A. The regulation of sleep and wakefulness by the hypothalamic neuropeptide orexin/hypocretin. Nagoya J Med Sci, 2013; 75: 29-36. IF=1.131; CI=24
6. *Fuller PM, *Yamanaka A, *Lazarus M. How genetically engineered systems are helping to define, and in some cases redefine, the neurobiological basis of sleep and wake. Temperature, 2015; 2: 406-417. doi: 10.1080/23328940.2015.1075095 IF=3.15; CI=8
7. Ono D, *Yamanaka A. Hypothalamic regulation of the sleep/wake cycle. Neurosci Res, 2017; 118: 74-81. doi: 10.1016/j.neures.2017.03.013 IF=3.304; CI=25
8. Black SW, Yamanaka A, *Kilduff TS. Challenges in the development of therapeutics for narcolepsy. Prog Neurobiol, 2017; 152: 89-113. doi: 10.1016/j.pneurobio.2015.12.002 IF=11.685; CI=26
9. Yamashita T, *Yamanaka A. Lateral hypothalamic circuits for sleep–wake control. Curr Opin Neurobiol, 2017; 44: 94-100. doi: 10.1016/j.conb.2017.03.020 IF=6.627; CI=30
10. *Ono D, Honma KI, Yanagawa Y, Yamanaka A, Honma S. Role of GABA in the regulation of the central circadian clock of the suprachiasmatic nucleus. J Physiol Sci, 2018; 68: 333-343. doi: 10.1007/s12576-018-0604-x IF=2.781; CI=26
11. Tisdale RK, Yamanaka A, *Kilduff TS. Animal models of narcolepsy and the hypocretin/orexin system: Past, present, and future. Sleep, 2021; 44(6): zsaa278. doi: 10.1093/sleep/zsaa278 IF=5.849; CI=1
12. Mukai Y, *Yamanaka A . Functional roles of REM sleep. Neurosci Res . 2022 Dec 23:S0168-0102(22)00299-1. doi: 10.1016/j.neures.2022.12.009. IF=2.904; CI=-
13. Hung C, *Yamanaka A. The role of orexin neuron activity in sleep/wakefulness regulation. Peptides. 2023 Apr 6:171007. doi: 10.1016/j.peptides.2023.171007. IF=3.867; CI=-
Book chapter:
1. *Yamanaka A. Afferent system of orexin neurons. In: The Orexin/Hypocretin System- Physiology and Pathophysiology. Nishino S, Sakurai T. (Eds.), 61-70, Humana Press, 2005.
2. *Yamanaka A, Tsunematsu T. Elucidation of neuronal circuitry involved in the regulation of sleep/wakefulness using optogenetics. In: Optogenetics: Light-Sensing Proteins and Their Applications, Kandori H, Koizumi A/. (Eds.), 249-264, Springer Japan, 2015.
3. *Yamanaka A, Yawo H. Neuroscientific frontline of optogenetics. In: Optogenetics: Light-Sensing Proteins and Their Applications, Kandori H, Koizumi A. (Eds.), 241-248, Springer Japan, 2015.
4. *Yamanaka A, Tsunematsu T. Elucidation of neuronal circuitry involved in the regulation of sleep/wakefulness using optogenetics. In: Orexin and Sleep. Sakurai T, Pandi-Perumal SR, Monti Jaime M. (Eds.), 81-92, Springer, 2015.
5. Chowdhury S, *Yamanaka A. Fiberless optogenetics. In: Optogenetics. Yawo H, Kandori H, Koizumi A, Kageyama R. (Eds.), 407-416, Springer Singapore, 2021.
